Why must blood groups match during transfusion?

    Short Answer

    Blood groups must match to prevent dangerous immune reactions that can damage red blood cells and endanger the patient's life.

    Detailed Explanation

    Red blood cells carry specific antigens on their surface. If a patient receives incompatible blood, their immune system recognizes these antigens as foreign and attacks the donated cells.

    This reaction can cause destruction of red blood cells (haemolysis), kidney damage, shock, or even death if not treated promptly.

    Matching both the ABO and Rh blood groups greatly reduces this risk and is a standard safety practice before every blood transfusion.

    Key Points

    • Incorrect blood matching can trigger severe immune reactions.
    • Both ABO and Rh compatibility are checked.
    • Hospitals always perform blood grouping and cross-matching.
    • Safe matching protects both patients and healthcare providers.

    ❤️ A carefully matched blood donation becomes a gift of life, not a risk. Your donation makes healing possible.

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