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For almost everyone, no. Your blood group remains the same throughout life.
A person's blood group is genetically determined before birth and normally remains unchanged throughout life.
In extremely rare medical situations—such as certain bone marrow transplants or severe blood disorders—the detected blood group may temporarily or permanently appear different. These situations are uncommon and occur under specialist medical care.
For healthy individuals, blood group never changes.
❤️ Your blood group stays constant—but every donation creates a lasting impact on someone's life.